PSMA8 - proteasome 20S subunit alpha 8 Gene

Homo sapiens

Also known as PSMA7L

Gene ID: 143471 | Gene type: protein coding

About PSMA8

Cytogenetic location: 18q11.2 Genomic coordinates (GRCh38): 18:26,133,869-26,193,355 (from NCBI)

This gene has 5 transcripts (splice variants), 197 orthologues and 18 paralogues. Restricted expression toward testis (RPKM 11.3).

Summary

Predicted to be involved in meiotic cell cycle and proteasomal protein catabolic process. Located in extracellular exosome and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PSMA8 Products(4)

mRNA	Protein	Name
NM_001025096.2	NP_001020267.1	proteasome subunit alpha-type 8 isoform 2
NM_001025097.2	NP_001020268.1	proteasome subunit alpha-type 8 isoform 3
NM_001308188.2	NP_001295117.1	proteasome subunit alpha-type 8 isoform 4
NM_144662.3	NP_653263.2	proteasome subunit alpha-type 8 isoform 1

PSMA8 Protein Structure

Proteasome_A_N

Proteasome

0
100
200
256 a.a.

Protein Preferred Names

Protein Names

proteasome subunit alpha-type 8

alpha4s

Related Diseases

Diseases

Alias

Cystic Fibrosis

Mucoviscidosis	CF
Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis	Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis
Cystic Fibrosis Lung Disease, Modifier Of	Cystic Fibrosis Of Pancreas
Fibrocystic Disease Of Pancreas	Cf - [Cystic Fibrosis]
Cystic Fibrosis Nos	Fibrocystic Disease
Fibrocystic Disease Of The Pancreas	Mucoviscidosis Of Pancreas
Nonproliferative Fibrocystic Disease	Pancreatic Cystic Fibrosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11298	PSMA8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PSMA8	VGNC	VGNC:104235
Felis catus	PSMA8	VGNC	VGNC:64412
Canis familiaris	PSMA8	VGNC	VGNC:45093
Bos taurus	PSMA8	VGNC	VGNC:33443
Mus musculus	PSMA8	MGD	MGI:1920927
Rattus norvegicus	PSMA8	RGD	RGD:1311659

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