Gas7 - growth arrest specific 7 Gene

Also Known as Gas7-cb; B230343A10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14457

Summary

Enables actin filament binding activity. Acts upstream of or within actin filament organization; neuron projection morphogenesis; and regulation of cell shape. Located in actin filament and ruffle. Is expressed in forebrain. Orthologous to human GAS7 (growth arrest specific 7). [provided by Alliance of Genome Resources, Apr 2022]

Gas7 Products (10)

mRNA Protein Name
NM_001109657.4 NP_001103127.1 growth arrest-specific protein 7 isoform b
NM_001277079.1 NP_001264008.1 growth arrest-specific protein 7 isoform c
NM_001277080.1 NP_001264009.1 growth arrest-specific protein 7 isoform d
NM_001402818.1 NP_001389747.1 growth arrest-specific protein 7 isoform e
NM_001402819.1 NP_001389748.1 growth arrest-specific protein 7 isoform f
NM_001402821.1 NP_001389750.1 growth arrest-specific protein 7 isoform c
NM_001402823.1 NP_001389752.1 growth arrest-specific protein 7 isoform d
NM_001402824.1 NP_001389753.1 growth arrest-specific protein 7 isoform d
NM_001402825.1 NP_001389754.1 growth arrest-specific protein 7 isoform g
NM_008088.5 NP_032114.2 growth arrest-specific protein 7 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin filament binding IDA
IDA: Inferred from direct assay
11795944 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin filament bundle assembly IDA
IDA: Inferred from direct assay
11795944 MGI
acts upstream of or within actin filament polymerization IDA
IDA: Inferred from direct assay
11795944 MGI
acts upstream of or within neuron differentiation IDA
IDA: Inferred from direct assay
15725398 MGI
acts upstream of or within neuron projection morphogenesis IMP
IMP: Inferred from mutant phenotype
9736752 MGI
acts upstream of or within regulation of cell shape IDA
IDA: Inferred from direct assay
11795944 MGI
Cellular Component GO Annotation Evidence References Source
located in actin filament IDA
IDA: Inferred from direct assay
11795944 MGI
located in ruffle IDA
IDA: Inferred from direct assay
11795944 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth arrest-specific protein 7

  • growth arrest-specific 7 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-164456 AMI-408 Inhibitor / Unkown
HY-RS05286 GAS7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07401 KMT2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19133 Gas7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25623 Gas7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gas7 NCBI NCBI:8522