Grb7 - growth factor receptor bound protein 7 Gene

Also Known as mKIAA4028

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14786

Summary

Predicted to enable identical protein binding activity; phosphatidylinositol binding activity; and protein kinase binding activity. Involved in negative regulation of translation and stress granule assembly. Located in cytoplasmic stress granule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human GRB7 (growth factor receptor bound protein 7). [provided by Alliance of Genome Resources, Apr 2022]

Grb7 Products (1)

mRNA Protein Name
NM_010346.2 NP_034476.1 growth factor receptor-bound protein 7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10521483 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of translation IMP
IMP: Inferred from mutant phenotype
18273060 MGI
involved in stress granule assembly IMP
IMP: Inferred from mutant phenotype
18273060 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
18273060 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth factor receptor-bound protein 7

  • GRB7 adapter protein

  • Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7)

  • epidermal growth factor receptor GRB-7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10224A G7-18NATE TFA 98.06% Unkown
HY-N14349 Asterriquinone Inhibitor / Unkown
HY-P10224 G7-18NATE / Unkown
HY-RS05781 GRB7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180480 NSC 104999 Ligand / Unkown
HY-180498 NSC 57148 Inhibitor / Unkown
HY-RS20748 Grb7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27260 Grb7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grb7 NCBI NCBI:2886