Gys1 - glycogen synthase 1, muscle Gene

Also Known as MGS; Gys3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14936

Summary

Enables glycogen (starch) synthase activity. Acts upstream of or within glycogen biosynthetic process and heart development. Located in cytoplasm and inclusion body. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in cardiovascular system disease. Orthologous to human GYS1 (glycogen synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Gys1 Products (1)

mRNA Protein Name
NM_030678.3 NP_109603.2 glycogen [starch] synthase, muscle

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity IDA
IDA: Inferred from direct assay
20300197 MGI
enables alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity IMP
IMP: Inferred from mutant phenotype
15282316 MGI
enables glycogen synthase activity, transferring glucose-1-phosphate IDA
IDA: Inferred from direct assay
17118331 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24142699 MGI
Biological Process GO Annotation Evidence References Source
involved in glycogen biosynthetic process IDA
IDA: Inferred from direct assay
21356517 MGI
acts upstream of or within glycogen biosynthetic process IMP
IMP: Inferred from mutant phenotype
15282316 MGI
involved in glycogen biosynthetic process IMP
IMP: Inferred from mutant phenotype
17118331 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
15282316 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17908927 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
9045612 MGI
located in inclusion body IDA
IDA: Inferred from direct assay
17908927 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycogen [starch] synthase, muscle

  • glycogen synthase 3, brain

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-156155 GYS1-IN-1 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-157646 MZ-101 99.42% Unkown
HY-RS05936 GYS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17956 Gys1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24427 Gys1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gys1 NCBI NCBI:2997