Hmga1 - high mobility group AT-hook 1 Gene
Also Known as Hmgi; Hmgy; Hmgiy; Hmga1a; Hmga1b
Species: Mus musculus
Gene Type: protein coding
Gene ID: 15361
Summary
This locus encodes a member of the nuclear, non-histone high mobility group protein family. This architectural transcription factor binds to A-T rich DNA sequences and participates in enhanceosome formation, chromatin remodeling and regulation of transcription. This protein functions in many cellular processes, including cell growth and differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
Hmga1 Products (63)
| mRNA | Protein | Name |
|---|---|---|
| NM_001025427.3 | NP_001020598.1 | high mobility group protein HMG-I/HMG-Y isoform a |
| NM_001039356.2 | NP_001034445.1 | high mobility group protein HMG-I/HMG-Y isoform a |
| NM_001166535.1 | NP_001160007.1 | high mobility group protein HMG-I/HMG-Y isoform a |
| NM_001166536.1 | NP_001160008.1 | high mobility group protein HMG-I/HMG-Y isoform a |
| NM_001166537.1 | NP_001160009.1 | high mobility group protein HMG-I/HMG-Y isoform b |
| NM_001166539.1 | NP_001160011.1 | high mobility group protein HMG-I/HMG-Y isoform b |
| NM_001166540.1 | NP_001160012.1 | high mobility group protein HMG-I/HMG-Y isoform b |
| NM_001166541.1 | NP_001160013.1 | high mobility group protein HMG-I/HMG-Y isoform b |
| NM_001166542.1 | NP_001160014.1 | high mobility group protein HMG-I/HMG-Y isoform b |
| NM_001166543.1 | NP_001160015.1 | high mobility group protein HMG-I/HMG-Y isoform c |
| NM_001166544.1 | NP_001160016.1 | high mobility group protein HMG-I/HMG-Y isoform c |
| NM_001166545.1 | NP_001160017.1 | high mobility group protein HMG-I/HMG-Y isoform d |
| NM_001166546.1 | NP_001160018.1 | high mobility group protein HMG-I/HMG-Y isoform e |
| NM_001412718.1 | NP_001399647.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412721.1 | NP_001399650.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412722.1 | NP_001399651.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412723.1 | NP_001399652.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412724.1 | NP_001399653.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412726.1 | NP_001399655.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412727.1 | NP_001399656.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412728.1 | NP_001399657.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412729.1 | NP_001399658.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412730.1 | NP_001399659.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412731.1 | NP_001399660.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412732.1 | NP_001399661.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412733.1 | NP_001399662.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412740.1 | NP_001399669.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412748.1 | NP_001399677.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412749.1 | NP_001399678.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412750.1 | NP_001399679.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412751.1 | NP_001399680.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412752.1 | NP_001399681.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412754.1 | NP_001399683.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412755.1 | NP_001399684.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412764.1 | NP_001399693.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412765.1 | NP_001399694.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412766.1 | NP_001399695.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412767.1 | NP_001399696.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412768.1 | NP_001399697.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412769.1 | NP_001399698.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412770.1 | NP_001399699.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412771.1 | NP_001399700.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412772.1 | NP_001399701.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412773.1 | NP_001399702.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412783.1 | NP_001399712.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412943.1 | NP_001399872.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412944.1 | NP_001399873.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412945.1 | NP_001399874.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412949.1 | NP_001399878.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412950.1 | NP_001399879.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412951.1 | NP_001399880.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412952.1 | NP_001399881.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412953.1 | NP_001399882.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412954.1 | NP_001399883.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412955.1 | NP_001399884.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412956.1 | NP_001399885.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412957.1 | NP_001399886.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412958.1 | NP_001399887.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001412959.1 | NP_001399888.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001413142.1 | NP_001400071.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001413143.1 | NP_001400072.1 | high mobility group protein HMG-I/HMG-Y |
| NM_001413144.1 | NP_001400073.1 | high mobility group protein HMG-I/HMG-Y |
| NM_016660.3 | NP_057869.2 | high mobility group protein HMG-I/HMG-Y isoform a |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables D-loop DNA binding |
IDA
IDA: Inferred from direct assay
|
15893306 | MGI |
| enables DNA binding |
IDA
IDA: Inferred from direct assay
|
22355763 | MGI |
| enables RNA polymerase II cis-regulatory region sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
19389484 | MGI |
| enables RNA polymerase II core promoter sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
15713121 | MGI |
| enables chromatin binding |
IDA
IDA: Inferred from direct assay
|
19389484 | MGI |
| enables minor groove of adenine-thymine-rich DNA binding |
IDA
IDA: Inferred from direct assay
|
19389484 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16870469 | MGI |
| enables transcription coactivator activity |
IDA
IDA: Inferred from direct assay
|
19389484 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of RNA polymerase II transcription regulator complex |
IDA
IDA: Inferred from direct assay
|
19389484 | MGI |
| part of SUMO ligase complex |
IDA
IDA: Inferred from direct assay
|
22207709 | MGI |
| is active in cytoplasm |
IDA
IDA: Inferred from direct assay
|
15893306 | MGI |
| located in male germ cell nucleus |
IDA
IDA: Inferred from direct assay
|
12032866 | MGI |
| is active in mitochondrion |
IDA
IDA: Inferred from direct assay
|
15893306 | MGI |
| is active in nucleus |
IDA
IDA: Inferred from direct assay
|
15893306 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
12032866 | MGI |
| is active in nucleus |
IPI
IPI: Inferred from physical interaction
|
16870469 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
high mobility group protein HMG-I/HMG-Y |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(4)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS06230 | HMGA1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS17912 | Hmga1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-184535 | PDIC-DPC | / | Unkown | |
| HY-RS24381 | Hmga1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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