Foxa3 - forkhead box A3 Gene

Also Known as Hnf3g; Tcf3g; Hnf-3g; Tcf-3g

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15377

Summary

Enables sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II and spermatogenesis. Acts upstream of or within several processes, including cellular glucose homeostasis; hematopoietic stem cell homeostasis; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; gut; and skeleton. Orthologous to human FOXA3 (forkhead box A3). [provided by Alliance of Genome Resources, Apr 2022]

Foxa3 Products (1)

mRNA Protein Name
NM_008260.2 NP_032286.1 hepatocyte nuclear factor 3-gamma

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7683413 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8306889 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to starvation IMP
IMP: Inferred from mutant phenotype
11546810 MGI
acts upstream of or within hematopoietic stem cell homeostasis IMP
IMP: Inferred from mutant phenotype
26880577 MGI
acts upstream of or within intracellular glucose homeostasis IMP
IMP: Inferred from mutant phenotype
11546810 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
19759516 MGI
acts upstream of or within regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
11546810 MGI
involved in regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17488644 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
17488644 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
19759516 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
8306889 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hepatocyte nuclear factor 3-gamma

  • HNF-3-gamma

  • forkhead box protein A3

  • hepatocyte nuclear factor 3 gamma (winged helix transcription factor)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-168534 WX-02-23 99.88% Unkown
HY-RS05038 FOXA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174678 Human FOXA3 mRNA / Unkown
HY-RS20927 Foxa3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27444 Foxa3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxa3 NCBI NCBI:3171