PSMD9 - Psmd9 proteasome 26S subunit, non-ATPase 9 Gene

Also Known as Bridge; Bridge-1

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 161475

Summary

Enables bHLH transcription factor binding activity; protein C-terminus binding activity; and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II; regulation of Insulin secretion; and type B pancreatic cell apoptotic process. Located in nucleus. Orthologous to human PSMD9 (Proteasome 26S subunit, non-ATPase 9). [provided by Alliance of Genome Resources, Apr 2022]

PSMD9 Products (1)

mRNA	Protein	Name
NM_130430.2	NP_569114.2	26S proteasome non-ATPase regulatory subunit 9

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables bHLH transcription factor binding	IDA IDA: Inferred from direct assay	10567574	RGD
enables bHLH transcription factor binding	IPI IPI: Inferred from physical interaction	10567574	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	10567574	RGD
enables transcription coactivator activity	IDA IDA: Inferred from direct assay	10567574	RGD

Biological Process GO Annotation	Evidence	References	Source
involved in negative regulation of insulin secretion	IMP IMP: Inferred from mutant phenotype	16099819	RGD
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	10567574	RGD
involved in positive regulation of insulin secretion	IDA IDA: Inferred from direct assay	10567574	RGD
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	10567574	RGD
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	10567574	RGD
involved in type B pancreatic cell apoptotic process	IMP IMP: Inferred from mutant phenotype	16099819	RGD

Cellular Component GO Annotation	Evidence	References	Source
located in nucleus	IDA IDA: Inferred from direct assay	10567574	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
26S proteasome non-ATPase regulatory subunit 9	26S proteasome non-ATPase regulatory subunit 9-like 26S proteasome regulatory subunit p27 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 transactivating protein Bridge-1

PSMD9 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	Psmd9	Q9WTV5	Pdx1	Rattus norvegicus	P52947	Pull Down	15885879

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11330	PSMD9 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	PSMD9	NCBI	NCBI:5715