Kcnma1 - potassium large conductance calcium-activated channel, subfamily M, alpha member 1 Gene
Also Known as Slo; BKCa; Slo1; mSlo; MaxiK; mSlo1; KCa1.1; slo-alpha; BKCA alpha; k(VCA)alpha; 5730414M22Rik
Species: Mus musculus
Summary
Enables identical protein binding activity; large conductance calcium-activated Potassium Channel activity; and voltage-gated Potassium Channel activity. Acts upstream of or within several processes, including adult walking behavior; eye blink reflex; and locomotor rhythm. Located in several cellular components, including apical plasma membrane; external side of plasma membrane; and postsynaptic membrane. Is integral component of membrane. Part of voltage-gated Potassium Channel complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in Alzheimer's disease and idiopathic generalized epilepsy. Orthologous to human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1). [provided by Alliance of Genome Resources, Apr 2022]
Kcnma1 Products (22)
| mRNA | Protein | Name |
|---|---|---|
| NM_001253358.1 | NP_001240287.1 | calcium-activated potassium channel subunit alpha-1 isoform 1 |
| NM_001253359.1 | NP_001240288.1 | calcium-activated potassium channel subunit alpha-1 isoform 2 |
| NM_001253360.1 | NP_001240289.1 | calcium-activated potassium channel subunit alpha-1 isoform 3 |
| NM_001253361.1 | NP_001240290.1 | calcium-activated potassium channel subunit alpha-1 isoform 4 |
| NM_001253362.1 | NP_001240291.1 | calcium-activated potassium channel subunit alpha-1 isoform 5 |
| NM_001253363.1 | NP_001240292.1 | calcium-activated potassium channel subunit alpha-1 isoform 6 |
| NM_001253364.1 | NP_001240293.1 | calcium-activated potassium channel subunit alpha-1 isoform 7 |
| NM_001253365.1 | NP_001240294.1 | calcium-activated potassium channel subunit alpha-1 isoform 9 |
| NM_001253366.1 | NP_001240295.1 | calcium-activated potassium channel subunit alpha-1 isoform 10 |
| NM_001253367.1 | NP_001240296.1 | calcium-activated potassium channel subunit alpha-1 isoform 11 |
| NM_001253368.1 | NP_001240297.1 | calcium-activated potassium channel subunit alpha-1 isoform 12 |
| NM_001253369.1 | NP_001240298.1 | calcium-activated potassium channel subunit alpha-1 isoform 13 |
| NM_001253370.1 | NP_001240299.1 | calcium-activated potassium channel subunit alpha-1 isoform 14 |
| NM_001253371.1 | NP_001240300.1 | calcium-activated potassium channel subunit alpha-1 isoform 15 |
| NM_001253372.1 | NP_001240301.1 | calcium-activated potassium channel subunit alpha-1 isoform 16 |
| NM_001253373.1 | NP_001240302.1 | calcium-activated potassium channel subunit alpha-1 isoform 17 |
| NM_001253374.1 | NP_001240303.1 | calcium-activated potassium channel subunit alpha-1 isoform 18 |
| NM_001253375.1 | NP_001240304.1 | calcium-activated potassium channel subunit alpha-1 isoform 19 |
| NM_001253376.1 | NP_001240305.1 | calcium-activated potassium channel subunit alpha-1 isoform 20 |
| NM_001253377.1 | NP_001240306.1 | calcium-activated potassium channel subunit alpha-1 isoform 21 |
| NM_001253378.1 | NP_001240307.1 | calcium-activated potassium channel subunit alpha-1 isoform 22 |
| NM_010610.3 | NP_034740.2 | calcium-activated potassium channel subunit alpha-1 isoform 8 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
calcium-activated potassium channel subunit alpha-1 |
|
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Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS07164 | KCNMA1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS20560 | Kcnma1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27069 | Kcnma1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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