TCF3 - Tcf3 transcription factor 3 Gene

Also Known as Pan2; Tcfe2a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171046

Summary

Enables PDZ domain binding activity and bHLH transcription factor binding activity. Contributes to E-box binding activity. Involved in positive regulation of gene expression and positive regulation of transcription, DNA-templated. Part of transcription regulator complex. Human ortholog(s) of this gene implicated in agammaglobulinemia and colorectal Cancer. Orthologous to human TCF3 (transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

TCF3 Products (2)

mRNA Protein Name
NM_001035237.1 NP_001030314.1 transcription factor E2-alpha isoform b
NM_133524.2 NP_598208.2 transcription factor E2-alpha isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to E-box binding IDA
IDA: Inferred from direct assay
19828133 RGD
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
10567574 RGD
enables bHLH transcription factor binding IPI
IPI: Inferred from physical interaction
10567574 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15831523 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
19828133 RGD
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
19828133 RGD
Cellular Component GO Annotation Evidence References Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
19828133 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor E2-alpha

  • TCF-3

  • immunoglobulin enhancer-binding factor E12/E47

  • pancreas specific transcription factor 1c

  • transcription factor E2a

  • transcription factor E2a-like

  • transcription regulator Pan

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14306 TCF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14309 TCF7L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183004 NCP26 / Unkown
HY-RS18501 Tcf3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24983 Tcf3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TCF3 NCBI NCBI:6929