Eef1a1 - eukaryotic translation elongation factor 1 alpha 1 Gene

Also Known as SI; EF1A; EEF-1; EEF1A; Eef1a2; Eef1a2l1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171361

Summary

Enables identical protein binding activity and mRNA binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; negative regulation of Reactive Oxygen Species biosynthetic process; and positive regulation of neuron projection development. Located in cytosol and nucleus. Orthologous to human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Eef1a1 Products (1)

mRNA Protein Name
NM_175838.2 NP_787032.1 elongation factor 1-alpha 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heterocyclic compound binding IPI
IPI: Inferred from physical interaction
18218611 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
19501573 RGD
enables mRNA binding IDA
IDA: Inferred from direct assay
19501573 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to nerve growth factor stimulus IEP
IEP: Inferred from expression pattern
11907030 RGD
involved in cellular response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
21390260 RGD
involved in negative regulation of reactive oxygen species biosynthetic process IMP
IMP: Inferred from mutant phenotype
23041468 RGD
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
16319173 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
21390260 RGD
involved in regulation of postsynaptic specialization assembly IDA
IDA: Inferred from direct assay
23839781 RGD
involved in regulation of postsynaptic specialization assembly IMP
IMP: Inferred from mutant phenotype
23839781 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
23839781 RGD
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
23839781 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
15265584 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

elongation factor 1-alpha 1

  • EF-1 alpha2

  • EF-1-alpha-1

  • EF-Tu

  • eEF1A-1

  • elongation factor 1 A-1

  • elongation factor Tu

  • eukaryotic elongation factor 1 A-1

  • eukaryotic translation elongation factor 1 alpha 2 like 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123035 Gamendazole Inhibitor 99.44% Unkown
HY-RS04174 EEF1A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04178 EEF1E1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18307 Eef1a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24785 Eef1a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eef1a1 NCBI NCBI:1915