Mnt - max binding protein Gene

Also Known as Rox; bHLHd3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17428

Summary

Enables DNA binding activity; DNA-binding transcription factor activity; and chromatin binding activity. Acts upstream of or within several processes, including cell aging; negative regulation of apoptotic signaling pathway; and regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; future brain; genitourinary system; and retina nuclear layer. Used to study Miller-Dieker lissencephaly syndrome. Orthologous to human MNT (MAX network transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]

Mnt Products (1)

mRNA Protein Name
NM_010813.3 NP_034943.3 max-binding protein MNT

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12970171 MGI
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
12970171 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
16103876 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16103876 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular senescence IMP
IMP: Inferred from mutant phenotype
12970171 MGI
acts upstream of or within negative regulation of apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
12970171 MGI
acts upstream of or within regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
12970171 MGI
acts upstream of or within regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
12970171 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

max-binding protein MNT

  • myc antagonist MNT

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N2983 Cajanin Inhibitor 99.96% Unkown
HY-RS08570 MNT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W112284 5,10,15,20-Tetra(1-methyl-4-pyridyl)porphyrin manganese / Unkown
HY-W130288 1-(1-Naphthyl)piperazine 99.62% Unkown
HY-RS19866 Mnt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26365 Mnt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mnt NCBI NCBI:4335