Pde6d - phosphodiesterase 6D, cGMP-specific, rod, delta Gene

Also Known as PrBP/delta

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18582

Summary

Enables GTPase inhibitor activity. Predicted to be involved in sensory perception of light stimulus. Predicted to act upstream of or within phototransduction. Predicted to be located in cytoplasmic vesicle and cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Joubert syndrome 22. Orthologous to human PDE6D (phosphodiesterase 6D). [provided by Alliance of Genome Resources, Apr 2022]

Pde6d Products (3)

mRNA Protein Name
NM_001360816.1 NP_001347745.1 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform 2
NM_001360817.1 NP_001347746.1 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform 3
NM_008801.3 NP_032827.1 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables GTPase inhibitor activity IDA
IDA: Inferred from direct assay
15979089 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9990021 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

  • GMP-PDE delta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145319 FPFT-2216 Inhibitor 99.55% Unkown
HY-145321 TMX-4100 Inhibitor 98.26% Unkown
HY-145320 TMX-4113 Inhibitor 99.08% Unkown
HY-RS10235 PDE6D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-163636 Deltaflexin3 Inhibitor / Unkown
HY-174379 KRAS IN-44 / Unkown
HY-175602 TM-04-064-02 Degrader / Unkown
HY-183717 M4K3233 / Unkown
HY-RS22712 Pde6d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29226 Pde6d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pde6d NCBI NCBI:5147