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Cat. No.: HY-163636

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Deltaflexin3

(Synonyms: A-442b)

Deltaflexin3 is a potent PDE6D inhibitor. Deltaflexin3 reduces the signaling of Ras and selectively decreases the KRAS mutant and PDE6D-dependent cancer cells growth.

For research use only. We do not sell to patients.

CAS No.: 2767277-64-3
Formula: C₂₅H₃₆FN₅O₂
Molecular Weight:457.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Deltaflexin3 Chemical Structure

CAS No.: 2767277-64-3

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Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Deltaflexin3 is a potent PDE6D inhibitor. Deltaflexin3 reduces the signaling of Ras and selectively decreases the KRAS mutant and PDE6D-dependent cancer cells growth^[1].

All Phosphodiesterase (PDE) Isoforms :

All Ras Isoforms :

Chemical Information

CAS No. 2767277-64-3
Molecular Weight 457.58
Formula C₂₅H₃₆FN₅O₂
SMILES

O=C(N(CCCCCCC(N(CC)CC1=NC(NC)=NC=C1)=O)C(C)C)C2=CC=C(F)C=C2
Synonyms

A-442b
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kaya P, et al. An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth. J Med Chem. 2024 May 17. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Deltaflexin3

All Phosphodiesterase (PDE) Isoforms

All Ras Isoforms