Pik3r3 - phosphoinositide-3-kinase regulatory subunit 3 Gene

Also Known as p55; p55pik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18710

Summary

Enables 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within Insulin Receptor signaling pathway. Part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in colon adenocarcinoma. Orthologous to human PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

Pik3r3 Products (4)

mRNA Protein Name
NM_001355584.1 NP_001342513.1 phosphatidylinositol 3-kinase regulatory subunit gamma isoform 1
NM_001355585.1 NP_001342514.1 phosphatidylinositol 3-kinase regulatory subunit gamma isoform 1
NM_001355586.1 NP_001342515.1 phosphatidylinositol 3-kinase regulatory subunit gamma isoform 2
NM_181585.6 NP_853616.1 phosphatidylinositol 3-kinase regulatory subunit gamma isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 1-phosphatidylinositol-3-kinase regulator activity IDA
IDA: Inferred from direct assay
7542745 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
7542745 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
7542745 MGI
Cellular Component GO Annotation Evidence References Source
part of phosphatidylinositol 3-kinase complex IPI
IPI: Inferred from physical interaction
7542745 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 3-kinase regulatory subunit gamma

  • PI3-kinase regulatory subunit gamma

  • PI3-kinase subunit p55-gamma

  • PI3K regulatory subunit gamma

  • phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)

  • phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma

  • ptdIns-3-kinase regula

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10538 PIK3R3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19801 Pik3r3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26297 Pik3r3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pik3r3 NCBI NCBI:8503