2. Gene
  3. Prkcq - protein kinase C, theta Gene

Prkcq - protein kinase C, theta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pkcq; PKC-0; PKCtheta; PKC-theta; A130035A12Rik

Gene ID: 18761 | Gene type: protein coding

About Prkcq

Chromosome 2: 11,176,919-11,306,033 forward strand.GRCm39:CM000995.3

This gene has 6 transcripts (splice variants), 204 orthologues, 5 paralogues and is associated with 57 phenotypes. Biased expression in testis adult (RPKM 34.4), thymus adult (RPKM 13.) and 6 other tissues.

Summary

Enables protein kinase C activity. Involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of cytokine production; and regulation of cell-cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell proliferation; positive regulation of interleukin-2 production; and protein phosphorylation. Located in cytoplasm and immunological synapse. Is expressed in several structures, including adipose tissue; genitourinary system; gut; limb; and nervous system. Used to study retinal detachment. Orthologous to human PRKCQ (protein kinase C theta). [provided by Alliance of Genome Resources, Apr 2022]

Prkcq Products(1)

mRNA Protein Name
NM_008859.2 NP_032885.1 protein kinase C theta type

Prkcq Protein Structure

C1_nPKC_theta-like_rpt1

C1_nPKC_theta-like_rpt1: cd20834 (152 - 212)

C1_nPKC_theta-like_rpt2

C1_nPKC_theta-like_rpt2: cd20837 (231 - 280)

STKc_nPKC_theta

STKc_nPKC_theta: cd05619 (373 - 703)

  • 0
  • 200
  • 400
  • 600
  • 707 a.a.
Protein Preferred Names Protein Names

protein kinase C theta type

PKC theta

nPKC-theta

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11137 PRKCQ Human Pre-designed siRNA Set A / Unkown
HY-RS11138 Prkcq Mouse Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkcq NCBI NCBI:5588