Ppp1cc - protein phosphatase 1 catalytic subunit gamma Gene

Also Known as PP1; PP-1G; dis2m1

Species: Mus musculus

Gene Type: protein coding

Gene ID: 19047

Summary

Enables protein serine/threonine Phosphatase activity. Involved in circadian regulation of gene expression; entrainment of circadian clock by photoperiod; and protein dephosphorylation. Acts upstream of or within regulation of nucleocytoplasmic transport. Located in mitochondrial outer membrane. Is expressed in several structures, including central nervous system and retina. Orthologous to human PPP1CC (protein Phosphatase 1 catalytic subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1cc Products (1)

mRNA	Protein	Name
NM_013636.4	NP_038664.2	serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables phosphatase activity	IDA IDA: Inferred from direct assay	21930935	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	12931191	MGI
enables protein serine/threonine phosphatase activity	IDA IDA: Inferred from direct assay	14640981	MGI
enables protein serine/threonine phosphatase activity	IMP IMP: Inferred from mutant phenotype	12931191	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within blastocyst development	IMP IMP: Inferred from mutant phenotype	12606345	MGI
involved in circadian regulation of gene expression	IDA IDA: Inferred from direct assay	21930935	MGI
involved in entrainment of circadian clock by photoperiod	IMP IMP: Inferred from mutant phenotype	21712997	MGI
acts upstream of or within protein dephosphorylation	IDA IDA: Inferred from direct assay	14640981	MGI
involved in protein dephosphorylation	IDA IDA: Inferred from direct assay	21930935	MGI
acts upstream of or within protein dephosphorylation	IMP IMP: Inferred from mutant phenotype	17369396	MGI
involved in regulation of circadian rhythm	IDA IDA: Inferred from direct assay	21930935	MGI
involved in regulation of circadian rhythm	IMP IMP: Inferred from mutant phenotype	21712997	MGI
acts upstream of or within regulation of nucleocytoplasmic transport	IMP IMP: Inferred from mutant phenotype	17369396	MGI
acts upstream of or within spermatogenesis	IMP IMP: Inferred from mutant phenotype	9882500	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in mitochondrial outer membrane	IDA IDA: Inferred from direct assay	12931191	MGI
located in mitochondrion	IDA IDA: Inferred from direct assay	12931191	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
serine/threonine-protein phosphatase PP1-gamma catalytic subunit	PP1C gamma 1 PP1C gamma 2 protein phosphatase 1C catalytic subunit

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10975	PPP1CC Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19803	Ppp1cc Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26299	Ppp1cc Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ppp1cc	NCBI	NCBI:5501