Prodh - proline dehydrogenase Gene

Also Known as Pro1; Pro-1; Ym24d07

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19125

Summary

Predicted to enable FAD binding activity; amino acid binding activity; and proline dehydrogenase activity. Predicted to be involved in positive regulation of cell death and proline catabolic process to glutamate. Predicted to act upstream of or within proline metabolic process. Located in mitochondrion. Is expressed in several structures, including adipose tissue; cardiovascular system; central nervous system; forelimb bud; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in amino acid metabolic disorder; hyperprolinemia type 1; and schizophrenia 4. Orthologous to human PRODH (proline dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Prodh Products (1)

mRNA Protein Name
NM_011172.2 NP_035302.2 proline dehydrogenase 1, mitochondrial precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
18775783 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proline dehydrogenase 1, mitochondrial

  • proline dehydrogenase, mitochondrial

  • proline oxidase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-142035 N-Propargylglycine 99.70% Unkown
HY-W016887 Glycyl-L-proline Inducer 99.88% Unkown
HY-111095S2 D-(-)-Lactic acid-13C-1 / Unkown
HY-RS11192 PRODH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11193 PRODH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21030 Prodh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27547 Prodh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prodh NCBI NCBI:5625