2. Gene
  3. B3GNT6 - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 Gene

B3GNT6 - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BGnT-6; B3Gn-T6; beta3Gn-T6; beta-1,3-Gn-T6

Gene ID: 192134 | Gene type: protein coding

About B3GNT6

Cytogenetic location: 11q13.5 Genomic coordinates (GRCh38): 11:77,034,398-77,041,973 (from NCBI)

This gene has 2 transcripts (splice variants), 803 orthologues and 15 paralogues. Biased expression in colon (RPKM 17.5), stomach (RPKM 11.9) and 4 other tissues.

Summary

The protein encoded by this gene is a beta-1,3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded Enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. [provided by RefSeq, Dec 2016]

B3GNT6 Products(1)

mRNA Protein Name
NM_138706.5 NP_619651.3 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
Protein Preferred Names Protein Names

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase

beta-1,3-N-acetylglucosaminyltransferase 6

Recombinant B3GNT6 Proteins

Cat. No. Product Name Accession Purity
HY-P76741 B3GNT6 Protein, Human (sf9, His) Q6ZMB0 (Q44-S384) ≥95%

Related Diseases

Diseases Alias
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Diseases Alias
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Waldenstroem'S Macroglobulinemia

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Lymphoplasmacytic Lymphoma

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Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01313 B3GNT6 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta B3GNT6 VGNC VGNC:70123
Bos taurus B3GNT6 VGNC VGNC:26382
Felis catus B3GNT6 VGNC VGNC:60058
Rattus norvegicus B3GNT6 RGD RGD:1310926
Canis familiaris B3GNT6 VGNC VGNC:49799
Mus musculus B3GNT6 MGD MGI:3039603
Others B3GNT6 NCBI