Ufsp2 - UFM1-specific peptidase 2 Gene

Also Known as 1810047C23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 192169

Summary

Enables UFM1 hydrolase activity and thiolester hydrolase activity. Acts upstream of or within proteolysis. Located in endoplasmic reticulum and nucleus. Is expressed in liver; orbito-sphenoid; pancreas epithelium; and turbinate bone primordium. Human ortholog(s) of this gene implicated in Beukes hip dysplasia. Orthologous to human UFSP2 (UFM1 specific peptidase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ufsp2 Products (1)

mRNA Protein Name
NM_138668.2 NP_619609.1 ufm1-specific protease 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables deUFMylase activity IDA
IDA: Inferred from direct assay
17182609 MGI
enables deUFMylase activity IMP
IMP: Inferred from mutant phenotype
33372156 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of type II interferon production IMP
IMP: Inferred from mutant phenotype
33372156 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21228277 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
21228277 MGI
located in nucleus IDA
IDA: Inferred from direct assay
21228277 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ufm1-specific protease 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15418 UFSP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21801 Ufsp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28317 Ufsp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ufsp2 NCBI NCBI:55325