Abcd4 - ATP-binding cassette, sub-family D (ALD), member 4 Gene

Also Known as P69r; P70R; Pxmp1l

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19300

Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that the human protein may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. [provided by RefSeq, Jul 2008]

Abcd4 Products (1)

mRNA Protein Name
NM_008992.2 NP_033018.2 lysosomal cobalamin transporter ABCD4
Protein Preferred Names Protein Names

lysosomal cobalamin transporter ABCD4

  • ATP-binding cassette sub-family D member 4

  • PMP69

  • PMP70-related protein

  • PXMP1-L

  • peroxisomal membrane protein 69

  • peroxisomal membrane protein, 70 kDa-related

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcd4 NCBI NCBI:5826