Rab1a - RAB1A, member RAS oncogene family Gene

Also Known as Gtbp; Rab1; Ypt1; Rab-1; mKIAA3012

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19324

Summary

Predicted to enable GTP binding activity and GTPase activity. Involved in cell migration; melanosome transport; and substrate adhesion-dependent cell spreading. Located in Golgi apparatus and melanosome. Is expressed in several structures, including diaphragm and genitourinary system. Used to study dilated cardiomyopathy. Orthologous to human RAB1A (RAB1A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab1a Products (1)

mRNA Protein Name
NM_008996.4 NP_033022.1 ras-related protein Rab-1A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24549040 MGI
Biological Process GO Annotation Evidence References Source
involved in cell migration IMP
IMP: Inferred from mutant phenotype
20639577 MGI
involved in melanosome transport IMP
IMP: Inferred from mutant phenotype
22854043 MGI
involved in substrate adhesion-dependent cell spreading IMP
IMP: Inferred from mutant phenotype
20639577 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
11042173 MGI
located in melanosome IDA
IDA: Inferred from direct assay
22854043 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-1A

  • RAB1, member RAS oncogene family

  • YPT1-related protein

  • ras-related YPT1 protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-16997 Itacitinib Inhibitor 99.97% Phase 3

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-110174 NAB2 Degrader 99.57% Unkown
HY-16997A Itacitinib adipate Inhibitor 99.18% Yes
HY-156242 BQZ-485 Inducer / Unkown
HY-RS11528 RAB1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22758 Rab1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29272 Rab1a Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab1a NCBI NCBI:5861