Rce1 - Ras converting CAAX endopeptidase 1 Gene

Also Known as D19Ertd98e; D19Ertd283e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19671

Summary

Predicted to enable exopeptidase activity and metalloendopeptidase activity. Predicted to be involved in CAAX-box protein processing and protein prenylation. Predicted to act upstream of or within proteolysis. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human RCE1 (Ras converting CAAX endopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Rce1 Products (5)

mRNA Protein Name
NM_001368712.1 NP_001355641.1 CAAX prenyl protease 2 isoform a
NM_001368713.1 NP_001355642.1 CAAX prenyl protease 2 isoform c
NM_001368714.1 NP_001355643.1 CAAX prenyl protease 2 isoform d
NM_001368715.1 NP_001355644.1 CAAX prenyl protease 2 isoform d
NM_023131.2 NP_075620.1 CAAX prenyl protease 2 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables endopeptidase activity IMP
IMP: Inferred from mutant phenotype
10085069 MGI
Biological Process GO Annotation Evidence References Source
involved in CAAX-box protein maturation IMP
IMP: Inferred from mutant phenotype
10085069 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CAAX prenyl protease 2

  • FACE-2

  • RCE1 homolog, prenyl protein peptidase

  • Ras and a-factor-converting enzyme 1 homolog

  • farnesylated proteins-converting enzyme 2

  • prenyl protein-specific endoprotease 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122079 NSC1011 / Unkown
HY-124126 NSC 1008 Inhibitor / Unkown
HY-RS11785 RCE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19943 Rce1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26445 Rce1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rce1 NCBI NCBI:9986