CYP4Z1 - cytochrome P450 family 4 subfamily Z member 1 Gene

Also Known as CYP4A20

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 199974

About CYP4Z1

Cytogenetic location: 1p33 Genomic coordinates (GRCh38): 1:47,055,525-47,118,318 (from NCBI)

This gene has 2 transcripts (splice variants), 328 orthologues and 12 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. This gene is part of a cluster of Cytochrome P450 genes on chromosome 1p33. [provided by RefSeq, Jul 2008]

CYP4Z1 Products (1)

mRNA Protein Name
NM_178134.3 NP_835235.1 cytochrome P450 4Z1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables arachidonate 14,15-epoxygenase activity IDA
IDA: Inferred from direct assay
29018033 GOA
enables fatty acid in-chain hydroxylase activity IDA
IDA: Inferred from direct assay
19090726 GOA
Biological Process GO Annotation Evidence References Source
involved in arachidonate metabolic process IDA
IDA: Inferred from direct assay
29018033 GOA
involved in lauric acid metabolic process IDA
IDA: Inferred from direct assay
19090726 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
15059886 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CYP4Z1 Protein Structure

p450

p450: Cytochrome P450 (47 - 497)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 505 a.a.
Protein Preferred Names Protein Names

cytochrome P450 4Z1

  • CYPIVZ1

Related Diseases

Diseases Alias
Bietti Crystalline Corneoretinal Dystrophy

  • BCD

  • Bietti Crystalline Dystrophy

  • Bietti Tapetoretinal Degeneration With Marginal Corneal Dystrophy

  • Bietti Crystalline Retinopathy

  • Bietti'S Crystalline Dystrophy

  • Crystalline Retinopathy

  • Dystrophy, Corneoretinal, Crystalline, Bietti
Breast Adenoma

  • Ademoma - Breast
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-152159 CYP4Z1-IN-1 Inhibitor / Unkown
HY-183756 CYP4Z1-IN-3 / Unkown
HY-RS03485 CYP4Z1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-139002 CYP4Z1-IN-2 Inhibitor / Unkown