Rps6 - ribosomal protein S6 Gene

Also Known as S6R

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20104

Summary

Predicted to enable protein kinase binding activity. Predicted to be a structural constituent of ribosome. Involved in glucose homeostasis. Acts upstream of or within several processes, including T cell activation; activation-induced cell death of T cells; and ribosome biogenesis. Located in dendrite; perinuclear region of cytoplasm; and ribosome. Part of cytosolic small ribosomal subunit and polysome. Is expressed in several structures, including early conceptus; forelimb; gonad; intestine epithelium; and salivary gland. Orthologous to human RPS6 (ribosomal protein S6). [provided by Alliance of Genome Resources, Apr 2022]

Rps6 Products (1)

mRNA Protein Name
NM_009096.3 NP_033122.1 40S ribosomal protein S6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21045808 MGI
enables structural constituent of ribosome IDA
IDA: Inferred from direct assay
36517592 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
10856218 MGI
acts upstream of or within T cell differentiation in thymus IGI
IGI: Inferred from genetic interaction
16357222 MGI
acts upstream of or within T cell differentiation in thymus IMP
IMP: Inferred from mutant phenotype
16357222 MGI
acts upstream of or within T cell proliferation involved in immune response IGI
IGI: Inferred from genetic interaction
16357222 MGI
acts upstream of or within T cell proliferation involved in immune response IMP
IMP: Inferred from mutant phenotype
16357222 MGI
acts upstream of or within activation-induced cell death of T cells IMP
IMP: Inferred from mutant phenotype
16357222 MGI
acts upstream of or within erythrocyte development IMP
IMP: Inferred from mutant phenotype
17000767 MGI
acts upstream of or within gastrulation IGI
IGI: Inferred from genetic interaction
17000767 MGI
acts upstream of or within gastrulation IMP
IMP: Inferred from mutant phenotype
17000767 MGI
involved in glucose homeostasis IDA
IDA: Inferred from direct assay
16166381 MGI
acts upstream of or within mammalian oogenesis stage IMP
IMP: Inferred from mutant phenotype
17000767 MGI
acts upstream of or within mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
17000767 MGI
acts upstream of or within mitotic cell cycle checkpoint signaling IMP
IMP: Inferred from mutant phenotype
16357222 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
17000767 MGI
acts upstream of or within placenta development IMP
IMP: Inferred from mutant phenotype
17000767 MGI
acts upstream of or within rRNA processing IMP
IMP: Inferred from mutant phenotype
16357222 MGI
acts upstream of or within ribosomal small subunit biogenesis IMP
IMP: Inferred from mutant phenotype
10856218 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12388085 MGI
part of cytosolic small ribosomal subunit IDA
IDA: Inferred from direct assay
23500592 MGI
located in dendrite IDA
IDA: Inferred from direct assay
22022532 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
16286931 MGI
located in ribosome IDA
IDA: Inferred from direct assay
14681305 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

40S ribosomal protein S6

  • phosphoprotein NP33

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (41)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123919 TL13-112 Inhibitor 98.01% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-13495 ML281 98.04% Unkown
HY-122582 TL13-12 Degrader 98.16% Unkown
HY-148061 DB1113 99.86% Unkown
HY-148062 RSS0680 Degrader 99.85% Unkown
HY-148063 DB0614 99.92% Unkown
HY-W070306 PDK1-IN-1 Inhibitor 99.95% Unkown
HY-RS12247 RPS6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-50733 CX-5011 free base / Unkown
HY-150643 RSK2-IN-2 Inhibitor / Unkown
HY-150717 RSK2-IN-3 Inhibitor / Unkown
HY-161874 RPS6-IN-1 / Unkown
HY-RS12248 RPS6KA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12249 Rps6ka1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12250 Rps6ka1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12251 RPS6KA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12252 Rps6ka2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12253 Rps6ka2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12254 RPS6KA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12255 Rps6ka3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12256 Rps6ka3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12257 RPS6KA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12258 RPS6KA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12259 RPS6KA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12260 Rps6ka6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12261 Rps6ka6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12262 RPS6KB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12263 Rps6kb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12264 Rps6kb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12265 RPS6KB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12266 Rps6kb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12267 Rps6kb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12268 RPS6KC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183393 NVP-BHS345 Inhibitor / Unkown
HY-RS17694 Rps6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22025 Rps6ka4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22026 Rps6ka5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24156 Rps6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28543 Rps6ka4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28544 Rps6ka5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6 NCBI NCBI:6194