Sord - sorbitol dehydrogenase Gene

Also Known as SDH; XDH; Sdh1; Sdh-1; Sodh-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20322

Summary

Enables L-iditol 2-dehydrogenase activity. Involved in flagellated sperm motility. Acts upstream of or within sorbitol metabolic process. Located in mitochondrion and motile cilium. Is expressed in several structures, including alimentary system; limb; liver; metanephros; and nervous system. Used to study cataract. Orthologous to human SORD (sorbitol dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Sord Products (1)

mRNA Protein Name
NM_146126.4 NP_666238.1 sorbitol dehydrogenase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables D-sorbitol dehydrogenase (acceptor) activity IDA
IDA: Inferred from direct assay
6626150 MGI
enables D-sorbitol dehydrogenase (acceptor) activity IMP
IMP: Inferred from mutant phenotype
9403062 MGI
enables D-xylulose reductase activity IDA
IDA: Inferred from direct assay
38160 MGI
enables L-iditol 2-dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
722274 MGI
enables L-iditol 2-dehydrogenase (NAD+) activity IMP
IMP: Inferred from mutant phenotype
9403062 MGI
Biological Process GO Annotation Evidence References Source
involved in D-glucuronate catabolic process to D-xylulose 5-phosphate IDA
IDA: Inferred from direct assay
38160 MGI
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
18799757 MGI
involved in fructose biosynthetic process IDA
IDA: Inferred from direct assay
18799757 MGI
involved in fructose biosynthetic process IMP
IMP: Inferred from mutant phenotype
9604875 MGI
acts upstream of or within sorbitol metabolic process IDA
IDA: Inferred from direct assay
722274 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
38160 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
18799757 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
18799757 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sorbitol dehydrogenase

  • L-iditol 2-dehydrogenase

  • polyol dehydrogenase

  • sorbitol dehydrogenase 1

  • xylitol dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13573 SORD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18973 Sord Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25462 Sord Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sord NCBI NCBI:6652