2. Gene
  3. Sfrp1 - secreted frizzled-related protein 1 Gene

Sfrp1 - secreted frizzled-related protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as sFRP-1; 2210415K03Rik

Gene ID: 20377 | Gene type: protein coding

About Sfrp1

Chromosome 8: 23,901,518-23,939,648 forward strand.GRCm39:CM001001.3

This gene has 1 transcript (splice variant), 223 orthologues, 15 paralogues and is associated with 15 phenotypes. Ubiquitous expression in kidney adult (RPKM 23.7), CNS E11.5 (RPKM 22.8) and 26 other tissues.

Summary

Predicted to enable several functions, including Wnt-protein binding activity; Frizzled binding activity; and heparin binding activity. Involved in several processes, including cellular response to X-ray; cellular response to estrogen stimulus; and negative regulation of B cell differentiation. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human SFRP1 (secreted Frizzled related protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sfrp1 Products(1)

mRNA Protein Name
NM_013834.3 NP_038862.2 secreted frizzled-related protein 1 precursor

Sfrp1 Protein Structure

CRD_SFRP1

CRD_SFRP1: cd07443 (51 - 174)

NTR_Sfrp1_like

NTR_Sfrp1_like: cd03580 (182 - 305)

  • 0
  • 100
  • 200
  • 314 a.a.
Protein Preferred Names Protein Names

secreted frizzled-related protein 1

secreted frizzled-related sequence protein 1

Recombinant Sfrp1 Proteins

Cat. No. Product Name Accession Purity
HY-P73413 SFRP1 Protein, Mouse (CHO, His) AAC53145.1 (S32-K314) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10858 WAY 316606 Inhibitor 99.69% Unkown
HY-10858A WAY 316606 hydrochloride Inhibitor / Unkown
HY-RS12772 SFRP1 Human Pre-designed siRNA Set A / Unkown
HY-RS12773 Sfrp1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS12774 Sfrp1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sfrp1 NCBI NCBI:6422