2. Gene
  3. Slc2a4 - solute carrier family 2 (facilitated glucose transporter), member 4 Gene

Slc2a4 - solute carrier family 2 (facilitated glucose transporter), member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as GT2; twgy; Glut4; Glut-4

Gene ID: 20528 | Gene type: protein coding

About Slc2a4

Chromosome 11: 69,833,365-69,839,014 reverse strand.GRCm39:CM001004.3

This gene has 8 transcripts (splice variants), 289 orthologues, 11 paralogues and is associated with 36 phenotypes. Biased expression in heart adult (RPKM 161.8), mammary gland adult (RPKM 97.3) and 12 other tissues.

Summary

Enables glucose transmembrane transporter activity. Involved in cellular response to Insulin stimulus. Acts upstream of or within several processes, including amylopectin biosynthetic process; brown fat cell differentiation; and glucose import in response to Insulin stimulus. Located in several cellular components, including cytoplasmic vesicle; extracellular exosome; and sarcolemma. Is integral component of plasma membrane. Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; brain; and genitourinary system. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC2A4 (solute carrier family 2 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a4 Products(2)

mRNA Protein Name
NM_009204.2 NP_033230.2 solute carrier family 2, facilitated glucose transporter member 4 isoform 1
NM_001359114.1 NP_001346043.1 solute carrier family 2, facilitated glucose transporter member 4 isoform 2

Slc2a4 Protein Structure

MFS_GLUT_Class1

MFS_GLUT_Class1: cd17431 (25 - 473)

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  • 509 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 4

glucose transporter type 4, insulin-responsive

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13170 SLC2A4 Human Pre-designed siRNA Set A / Unkown
HY-RS13171 Slc2a4 Mouse Pre-designed siRNA Set A / Unkown
HY-RS13172 Slc2a4 Rat Pre-designed siRNA Set A / Unkown
HY-RS13173 SLC2A4RG Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc2a4 NCBI NCBI:6517