Sp100 - nuclear antigen Sp100 Gene

Also Known as A430075G10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20684

Summary

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; chromo shadow domain binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including innate immune response; regulation of signal transduction; and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nuclear lumen. Predicted to be part of Mre11 complex. Predicted to be active in nucleus. Is expressed in eye; olfactory placode; and otic pit. Orthologous to human SP100 (SP100 nuclear antigen). [provided by Alliance of Genome Resources, Apr 2022]

Sp100 Products (12)

mRNA Protein Name
NM_001313712.1 NP_001300641.1 nuclear autoantigen Sp-100 isoform 2
NM_001313713.1 NP_001300642.1 nuclear autoantigen Sp-100 isoform 3
NM_001313714.1 NP_001300643.1 nuclear autoantigen Sp-100 isoform 4
NM_001372231.1 NP_001359160.1 nuclear autoantigen Sp-100 isoform 5
NM_001372232.1 NP_001359161.1 nuclear autoantigen Sp-100 isoform 6
NM_013673.4 NP_038701.2 nuclear autoantigen Sp-100 isoform 1
NM_001313712.1 NP_001300641.1 nuclear autoantigen Sp-100 isoform 2
NM_001313713.1 NP_001300642.1 nuclear autoantigen Sp-100 isoform 3
NM_001313714.1 NP_001300643.1 nuclear autoantigen Sp-100 isoform 4
NM_001372231.1 NP_001359160.1 nuclear autoantigen Sp-100 isoform 5
NM_001372232.1 NP_001359161.1 nuclear autoantigen Sp-100 isoform 6
NM_013673.4 NP_038701.2 nuclear autoantigen Sp-100 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9636146 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear autoantigen Sp-100

  • nuclear dot-associated Sp100 protein

  • speckled 100 kDa

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-A0084 Procainamide hydrochloride 99.52% Unkown
HY-A0084A Procainamide 99.80% Unkown

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-A0084AS Procainamide-d4 / Unkown
HY-A0084S Procainamide-d4 hydrochloride / Unkown
HY-RS13601 SP100 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18297 Sp100 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24775 Sp100 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sp100 NCBI NCBI:6672