FABP7 - fatty acid binding protein 7 Gene

Homo sapiens

Also known as MRG; BLBP; FABPB; B-FABP

Gene ID: 2173 | Gene type: protein coding

About FABP7

Cytogenetic location: 6q22.31 Genomic coordinates (GRCh38): 6:122,749,201-122,784,074 (from NCBI)

This gene has 2 transcripts (splice variants), 283 orthologues and 15 paralogues. Biased expression in brain (RPKM 8.9) and skin (RPKM 0.4).

Summary

The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016]

FABP7 Products(4)

mRNA	Protein	Name
NM_001319039.2	NP_001305968.1	fatty acid-binding protein, brain isoform 2
NM_001319041.2	NP_001305970.1	fatty acid-binding protein, brain isoform 3
NM_001319042.2	NP_001305971.1	fatty acid-binding protein, brain isoform 4
NM_001446.5	NP_001437.1	fatty acid-binding protein, brain isoform 1

FABP7 Protein Structure

Lipocalin

0
100
132 a.a.

Protein Preferred Names

Protein Names

fatty acid-binding protein, brain

brain lipid-binding protein

Recombinant FABP7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7666	FABP7 Protein, Human (His)	O15540 (V2-A132)	≥95%
HY-P70200	Recombinant Human Fatty acid-binding protein/FABP7, His	O15540	≥95%

Related Diseases

Diseases

Alias

Adult Central Nervous System Primitive Neuroectodermal Neoplasm

Adult Cns Pnet

Adult Central Nervous System Primitive Neuroectodermal Tumor

High Grade Glioma

Malignant Glioma	Glial Cell Tumor
Glioma, Malignant	Malignant Neuroglial Tumor
Neuroglial Tumor	Glioma
Malignant Gliomas

Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma	RCC
Nonpapillary Renal Cell Carcinoma	Clear Cell Renal Cell Carcinoma
Hypernephroma	Adenocarcinoma Of Kidney
Renal Carcinoma, Chromophobe, Somatic	Clear Cell Carcinoma Of Kidney
Clear-Cell Metastatic Renal Cell Carcinoma	Clear Cell Renal Carcinoma
Renal Cell Carcinoma, Somatic	Conventional Renal Cell Carcinoma
Conventional Renal Cell Carcinoma	Renal Clear Cell Carcinoma
Ccrcc	Hereditary Clear Cell Renal Cell Carcinoma
Carcinoma, Renal Cell	Renal Cell Carcinoma, Clear Cell, Somatic
Renal Cell Carcinoma, Clear Cell	Clear Cell Kidney Carcinoma
Clear Cell Rcc	Cystic-Multilocular Variant
Clear Cell Renal Cell Adenocarcinoma	Hereditary Clear Cell Renal Cell Adenocarcinoma
Common Renal Cell Carcinoma	Crcc
Renal Cell Carcinoma Non-Papillary	Carcinoma Renal Cell
Renal Cell Cancer	Carcinoma, Renal Cell, Nonpapillary

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Hirschsprung Disease 1

Hirschsprung Disease	Aganglionic Megacolon
Hscr	Hirschsprung'S Disease
Congenital Megacolon	Congenital Intestinal Aganglionosis
Colonic Aganglionosis	Hirschsprung Disease, Susceptibility To, 1
Hirschsprung Disease, Protection Against	HSCR1
Mgc	Pelvirectal Achalasia
Total Intestinal Aganglionosis	Megacolon, Aganglionic
Macrocolon	Hscr 1
Hirschsprung Disease Type 1	Hirschsprung Disease, Type 1
Congenital Dilatation Of Colon	Aganglionosis
Congenital Aganglionic Megacolon	Aganglionosis Of Colon
Bowel Aganglionosis	Colon Aganglionosis
Hirschsprung Megacolon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-145990	FABPs ligand 6	Inhibitor	98.57%	Unkown
HY-RS04663	FABP7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	FABP7	VGNC	VGNC:28699
Canis familiaris	FABP7	VGNC	VGNC:40563
Felis catus	FABP7	VGNC	VGNC:62037
Macaca mulatta	FABP7	VGNC	VGNC:104376
Mus musculus	FABP7	MGD	MGI:101916
Rattus norvegicus	FABP7	RGD	RGD:69312
Others	FABP7	NCBI

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