Rasa1 - RAS p21 protein activator 1 Gene

Also Known as Gap; Rasa; RasGAP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 218397

Summary

Predicted to enable several functions, including GTPase activator activity; enzyme binding activity; and phosphotyrosine residue binding activity. Predicted to be involved in several processes, including activation of GTPase activity; cellular response to growth factor stimulus; and positive regulation of glucose import. Located in plasma membrane and ruffle. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in arteriovenous malformation and basal cell carcinoma. Orthologous to human RASA1 (Ras p21 protein activator 1). [provided by Alliance of Genome Resources, Apr 2022]

Rasa1 Products (1)

mRNA Protein Name
NM_145452.4 NP_663427.2 ras GTPase-activating protein 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9008161 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
15860730 MGI
located in ruffle IDA
IDA: Inferred from direct assay
15860730 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras GTPase-activating protein 1

  • GTPase-activating protein

  • p120-rasGAP

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11678 RASA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14089 SYNGAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22767 Rasa1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rasa1 NCBI NCBI:5921