MPEG1 - macrophage expressed 1 Gene
Also Known as P-2; MPG1; MPS1; IMD77; Mpg-1
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 219972
About MPEG1
Cytogenetic location: 11q12.1
Genomic coordinates (GRCh38): 11:59,208,510-59,212,927 (from NCBI)
This gene has 1 transcript (splice variant), 237 orthologues and is associated with 1 phenotype.
Summary
Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in cytoplasmic vesicle. Implicated in primary immunodeficiency disease. [provided by Alliance of Genome Resources, Apr 2022]
MPEG1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001039396.2 | NP_001034485.1 | macrophage-expressed gene 1 protein precursor |
MPEG1 Protein Structure
MACPF
MACPF: MAC/Perforin domain (126 - 341)
- 0
- 200
- 400
- 600
- 716 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
macrophage-expressed gene 1 protein |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Immunodeficiency 77 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(4)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-114512 | m-PEG1-NHS ester | 95.0% | Unkown | |
| HY-RS08610 | MPEG1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS20991 | Mpeg1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27508 | Mpeg1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | MPEG1 | VGNC | VGNC:101354 |
| Rattus norvegicus | MPEG1 | RGD | RGD:69275 |
| Felis catus | MPEG1 | VGNC | VGNC:63570 |
| Canis familiaris | MPEG1 | VGNC | VGNC:43333 |
| Mus musculus | MPEG1 | MGD | MGI:1333743 |
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