U2af2 - U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 Gene

Also Known as 65kDa

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22185

Summary

Enables C2H2 zinc finger domain binding activity. Involved in RNA splicing. Predicted to be located in nucleus. Predicted to be part of Prp19 complex; U2-type spliceosomal complex; and U2AF complex. Predicted to be active in nuclear speck. Is expressed in several structures, including alimentary system; central nervous system; liver lobe; lower urinary tract; and nose. Orthologous to human U2AF2 (U2 small nuclear RNA auxiliary factor 2). [provided by Alliance of Genome Resources, Apr 2022]

U2af2 Products (15)

mRNA Protein Name
NM_001205231.2 NP_001192160.1 splicing factor U2AF 65 kDa subunit isoform 1
NM_001403145.1 NP_001390074.1 splicing factor U2AF 65 kDa subunit isoform 3
NM_001403146.1 NP_001390075.1 splicing factor U2AF 65 kDa subunit isoform 4
NM_001403147.1 NP_001390076.1 splicing factor U2AF 65 kDa subunit isoform 5
NM_001403148.1 NP_001390077.1 splicing factor U2AF 65 kDa subunit isoform 6
NM_001403149.1 NP_001390078.1 splicing factor U2AF 65 kDa subunit isoform 6
NM_001403150.1 NP_001390079.1 splicing factor U2AF 65 kDa subunit isoform 7
NM_001403151.1 NP_001390080.1 splicing factor U2AF 65 kDa subunit isoform 7
NM_001403153.1 NP_001390082.1 splicing factor U2AF 65 kDa subunit isoform 7
NM_001403154.1 NP_001390083.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_001403155.1 NP_001390084.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_001403156.1 NP_001390085.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_001403158.1 NP_001390087.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_001403159.1 NP_001390088.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_133671.4 NP_598432.2 splicing factor U2AF 65 kDa subunit isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables C2H2 zinc finger domain binding IPI
IPI: Inferred from physical interaction
9784496 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16819553 MGI
Biological Process GO Annotation Evidence References Source
involved in RNA splicing IDA
IDA: Inferred from direct assay
9784496 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

splicing factor U2AF 65 kDa subunit

  • U2 auxiliary factor 65 kDa subunit

  • U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa

  • U2 snRNP auxiliary factor large subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153736 NSC 194308 99.86% Unkown
HY-RS15314 U2AF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22890 U2af2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29404 U2af2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens U2af2 NCBI NCBI:11338