2. Gene
  3. U2af2 - U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 Gene

U2af2 - U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 65kDa

Gene ID: 22185 | Gene type: protein coding

About U2af2

Summary

Enables C2H2 zinc finger domain binding activity. Involved in RNA splicing. Predicted to be located in nucleus. Predicted to be part of Prp19 complex; U2-type spliceosomal complex; and U2AF complex. Predicted to be active in nuclear speck. Is expressed in several structures, including alimentary system; central nervous system; liver lobe; lower urinary tract; and nose. Orthologous to human U2AF2 (U2 small nuclear RNA auxiliary factor 2). [provided by Alliance of Genome Resources, Apr 2022]

U2af2 Products(15)

mRNA Protein Name
NM_001205231.2 NP_001192160.1 splicing factor U2AF 65 kDa subunit isoform 1
NM_001403145.1 NP_001390074.1 splicing factor U2AF 65 kDa subunit isoform 3
NM_001403146.1 NP_001390075.1 splicing factor U2AF 65 kDa subunit isoform 4
NM_001403147.1 NP_001390076.1 splicing factor U2AF 65 kDa subunit isoform 5
NM_001403148.1 NP_001390077.1 splicing factor U2AF 65 kDa subunit isoform 6
NM_001403149.1 NP_001390078.1 splicing factor U2AF 65 kDa subunit isoform 6
NM_001403150.1 NP_001390079.1 splicing factor U2AF 65 kDa subunit isoform 7
NM_001403151.1 NP_001390080.1 splicing factor U2AF 65 kDa subunit isoform 7
NM_001403153.1 NP_001390082.1 splicing factor U2AF 65 kDa subunit isoform 7
NM_001403154.1 NP_001390083.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_001403155.1 NP_001390084.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_001403156.1 NP_001390085.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_001403158.1 NP_001390087.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_001403159.1 NP_001390088.1 splicing factor U2AF 65 kDa subunit isoform 8
NM_133671.4 NP_598432.2 splicing factor U2AF 65 kDa subunit isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables C2H2 zinc finger domain binding IPI
IPI: Inferred from physical interaction
9784496 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16819553 MGI
Biological Process GO Annotation Evidence Reference Source
involved in RNA splicing IDA
IDA: Inferred from direct assay
9784496 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

splicing factor U2AF 65 kDa subunit

U2 auxiliary factor 65 kDa subunit

U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa

U2 snRNP auxiliary factor large subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153736 NSC 194308 99.86% Unkown
HY-RS15314 U2AF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22890 U2af2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29404 U2af2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens U2af2 NCBI NCBI:11338