Vnn1 - vanin 1 Gene

Also Known as V-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22361

Summary

Predicted to enable pantetheine hydrolase activity. Involved in several processes, including chronic inflammatory response; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and positive regulation of T cell differentiation in thymus. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; facial bone primordium; genitourinary system; nervous system; and respiratory system. Orthologous to human VNN1 (vanin 1). [provided by Alliance of Genome Resources, Apr 2022]

Vnn1 Products (1)

mRNA Protein Name
NM_011704.3 NP_035834.2 pantetheinase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables pantetheine hydrolase activity IDA
IDA: Inferred from direct assay
11042271 MGI
Biological Process GO Annotation Evidence References Source
involved in acute inflammatory response IDA
IDA: Inferred from direct assay
14966568 MGI
involved in cell-cell adhesion IDA
IDA: Inferred from direct assay
8934567 MGI
involved in chronic inflammatory response IDA
IDA: Inferred from direct assay
14966568 MGI
involved in coenzyme A catabolic process IMP
IMP: Inferred from mutant phenotype
11042271 MGI
involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
15282320 MGI
involved in innate immune response IDA
IDA: Inferred from direct assay
14966568 MGI
involved in positive regulation of T cell differentiation in thymus IDA
IDA: Inferred from direct assay
8934567 MGI
involved in positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
15282320 MGI
Cellular Component GO Annotation Evidence References Source
NOT located in extracellular space IDA
IDA: Inferred from direct assay
11491533 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pantetheinase

  • pantetheine hydrolase

  • vascular non-inflammatory molecule 1

Recombinant Vnn1 Proteins

Cat. No. Product Name Accession Purity
HY-P76126 VNN1/Vanin-1 Protein, Mouse (HEK293, Fc) Q9Z0K8 (M1-S487) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P76127 VNN1/Vanin-1 Protein, Mouse (HEK293, His) Q9Z0K8 (L24-N488) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-168981 Larubrilstat Inhibitor 98.89% Unkown
HY-RS15666 VNN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18797 Vnn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25286 Vnn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vnn1 NCBI NCBI:8876