Vtn - vitronectin Gene

Also Known as Vn

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 22370

Summary

Enables extracellular matrix binding activity. Involved in oligodendrocyte differentiation. Acts upstream of or within cell-matrix adhesion; extracellular matrix organization; and positive regulation of cell-substrate adhesion. Located in extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; metanephros; and retina. Human ortholog(s) of this gene implicated in Churg-Strauss syndrome; granulomatosis with polyangiitis; and thrombosis. Orthologous to human VTN (Vitronectin). [provided by Alliance of Genome Resources, Apr 2022]

Vtn Products (1)

mRNA Protein Name
NM_011707.2 NP_035837.1 vitronectin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables extracellular matrix binding IDA
IDA: Inferred from direct assay
18757743 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within cell-matrix adhesion IDA
IDA: Inferred from direct assay
15728191 MGI
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
18757743 MGI
involved in oligodendrocyte differentiation IDA
IDA: Inferred from direct assay
23155445 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
18757743 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in extracellular matrix IDA
IDA: Inferred from direct assay
15728191 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vitronectin

  • S-protein

  • serum-spreading factor

Recombinant Vtn Proteins

製品番号 製品名 アクセッション番号 純度
HY-P73484 Vitronectin Protein, Mouse (HEK293, His) P29788 (D20-K478) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS15724 VTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17681 Vtn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24142 Vtn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Vtn NCBI NCBI:7448