Adcy5 - adenylate cyclase 5 Gene
Also Known as Ac5
Species: Mus musculus
Summary
Enables Adenylate Cyclase activity; Adenylate Cyclase binding activity; and scaffold protein binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway; locomotory behavior; and neuromuscular process controlling balance. Located in cilium and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study Parkinson's disease. Orthologous to human ADCY5 (Adenylate Cyclase 5). [provided by Alliance of Genome Resources, Apr 2022]
Adcy5 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001012765.5 | NP_001012783.3 | adenylate cyclase type 5 |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables adenylate cyclase activity |
IDA
IDA: Inferred from direct assay
|
17593019 | MGI |
| enables adenylate cyclase activity |
IMP
IMP: Inferred from mutant phenotype
|
12223546 | MGI |
| enables adenylate cyclase binding |
IPI
IPI: Inferred from physical interaction
|
18164588 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
17593019 | MGI |
| enables scaffold protein binding |
IPI
IPI: Inferred from physical interaction
|
19574217 | MGI |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| acts upstream of or within G protein-coupled adenosine receptor signaling pathway |
IGI
IGI: Inferred from genetic interaction
|
12223546 | MGI |
| acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway |
IGI
IGI: Inferred from genetic interaction
|
12223546 | MGI |
| acts upstream of or within adenylate cyclase-activating dopamine receptor signaling pathway |
IGI
IGI: Inferred from genetic interaction
|
12223546 | MGI |
| acts upstream of or within adenylate cyclase-inhibiting dopamine receptor signaling pathway |
IGI
IGI: Inferred from genetic interaction
|
12223546 | MGI |
| acts upstream of or within locomotory behavior |
IMP
IMP: Inferred from mutant phenotype
|
12665504 | MGI |
| acts upstream of or within neuromuscular process controlling balance |
IMP
IMP: Inferred from mutant phenotype
|
12665504 | MGI |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| located in cilium |
IDA
IDA: Inferred from direct assay
|
21670265 | MGI |
| located in membrane |
IDA
IDA: Inferred from direct assay
|
17593019 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
12665504 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
adenylate cyclase type 5 |
|
|