Mapkap1 - mitogen-activated protein kinase associated protein 1 Gene

Also Known as Sin1; D230039K05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 227743

Summary

Predicted to enable enzyme binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phospholipid binding activity. Involved in positive regulation of peptidyl-serine phosphorylation and regulation of cellular response to oxidative stress. Part of TORC2 complex. Is expressed in genitourinary system; gut gland; heart; and nervous system. Orthologous to human MAPKAP1 (MAPK associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Mapkap1 Products (6)

mRNA Protein Name
NM_001290625.1 NP_001277554.1 target of rapamycin complex 2 subunit MAPKAP1 isoform a
NM_001290626.1 NP_001277555.1 target of rapamycin complex 2 subunit MAPKAP1 isoform b
NM_001362919.1 NP_001349848.1 target of rapamycin complex 2 subunit MAPKAP1 isoform a
NM_001362920.1 NP_001349849.1 target of rapamycin complex 2 subunit MAPKAP1 isoform b
NM_001362921.1 NP_001349850.1 target of rapamycin complex 2 subunit MAPKAP1 isoform c
NM_177345.4 NP_796319.1 target of rapamycin complex 2 subunit MAPKAP1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21045808 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of peptidyl-serine phosphorylation IMP
IMP: Inferred from mutant phenotype
16962653 MGI
involved in regulation of cellular response to oxidative stress IMP
IMP: Inferred from mutant phenotype
16962653 MGI
Cellular Component GO Annotation Evidence References Source
part of TORC2 complex IDA
IDA: Inferred from direct assay
16962653 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

target of rapamycin complex 2 subunit MAPKAP1

  • SAPK-interacting protein 1

  • TORC2 subunit MAPKAP1

  • mitogen-activated protein kinase 2-associated protein 1

  • stress-activated map kinase-interacting protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-176166 PD-M6 98.17% Unkown
HY-N1190 DL-Syringaresinol Inhibitor 96% Unkown
HY-RS08130 MAPKAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22009 Mapkap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28527 Mapkap1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapkap1 NCBI NCBI:79109