Rnf40 - ring finger protein 40 Gene

Also Known as BRE1-B; mKIAA0661

Species: Mus musculus

Gene Type: protein coding
Gene ID: 233900

Summary

Predicted to enable several functions, including enzyme binding activity; protein homodimerization activity; and syntaxin-1 binding activity. Involved in positive regulation of histone H2B ubiquitination. Predicted to be located in axon terminus; cytosol; and nucleoplasm. Predicted to be extrinsic component of membrane. Predicted to be part of HULC complex and ubiquitin Ligase complex. Is expressed in genitourinary system and islets of Langerhans. Orthologous to human RNF40 (ring finger protein 40). [provided by Alliance of Genome Resources, Apr 2022]

Rnf40 Products (2)

mRNA Protein Name
NM_001360883.1 NP_001347812.1 E3 ubiquitin-protein ligase BRE1B isoform 2
NM_172281.2 NP_758485.2 E3 ubiquitin-protein ligase BRE1B isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22252316 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase BRE1B

  • RING-type E3 ubiquitin transferase BRE1B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W854844A (E)-JP-2-196 TFA Ligand 97.89% Unkown
HY-RS12091 RNF40 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21037 Rnf40 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27554 Rnf40 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf40 NCBI NCBI:9810