Gadd45g - growth arrest and DNA-damage-inducible 45 gamma Gene

Also Known as CR6; DDIT2; OIG37

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23882

Summary

Enables identical protein binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within negative regulation of protein kinase activity; positive regulation of MAPK cascade; and regulation of cell cycle. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human GADD45G (growth arrest and DNA damage inducible gamma). [provided by Alliance of Genome Resources, Apr 2022]

Gadd45g Products (1)

mRNA Protein Name
NM_011817.2 NP_035947.2 growth arrest and DNA damage-inducible protein GADD45 gamma

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
18445651 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11022036 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of protein kinase activity IDA
IDA: Inferred from direct assay
12124778 MGI
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: Inferred from direct assay
12213961 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
25071184 MGI
acts upstream of or within regulation of cell cycle IDA
IDA: Inferred from direct assay
12124778 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth arrest and DNA damage-inducible protein GADD45 gamma

  • cytokine-responsive protein CR6

  • growth arrest and DNA-damage-inducible, gamma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05231 GADD45G Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19838 Gadd45g Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26335 Gadd45g Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gadd45g NCBI NCBI:10912