Ggn - gametogenetin Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 243897

Summary

Enables identical protein binding activity and ubiquitin protein Ligase binding activity. Acts upstream of or within several processes, including double-strand break repair; embryo implantation; and gamete generation. Located in nucleolus and perinuclear region of cytoplasm. Is expressed in brain; early conceptus; eye; gonad; and metanephros. Orthologous to human GGN (gametogenetin). [provided by Alliance of Genome Resources, Apr 2022]

Ggn Products (3)

mRNA Protein Name
NM_001358852.1 NP_001345781.1 gametogenetin isoform 4
NM_182694.2 NP_874353.2 gametogenetin isoform 1
NM_182696.3 NP_874355.1 gametogenetin isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
14982849 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12574169 MGI
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
23451117 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within double-strand break repair IMP
IMP: Inferred from mutant phenotype
23451117 MGI
acts upstream of or within embryo implantation IMP
IMP: Inferred from mutant phenotype
23451117 MGI
involved in gamete generation IEP
IEP: Inferred from expression pattern
12574169 MGI
acts upstream of or within protein localization IDA
IDA: Inferred from direct assay
14982849 MGI
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15642376 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gametogenetin

Ggn Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Ggn Q80WJ1 Ggnbp2 Mus musculus Q5SV77
Y2H
15642376
Intra
Ggn Q80WJ1 Ggnbp2 Mus musculus Q5SV77
IF
15642376
Intra
Ggn Q80WJ1 Ggnbp2 Mus musculus Q5SV77
Anti Tag CoIP
15642376
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05400 GGN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20238 Ggn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26745 Ggn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ggn NCBI NCBI:199720