Mtnr1b - melatonin receptor 1B Gene
Also Known as Mt2; Mel1b; Mel-1B-R
Species: Mus musculus
About Mtnr1b
This gene has 2 transcripts (splice variants), 106 orthologues, 55 paralogues and is associated with 5 phenotypes. Low expression observed in reference dataset.
Summary
Predicted to enable Melatonin Receptor activity. Predicted to be involved in several processes, including negative regulation of cGMP-mediated signaling; negative regulation of transport; and regulation of transmission of nerve impulse. Predicted to act upstream of or within circadian rhythm. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Is expressed in central nervous system; eye; gut; and reproductive system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (Melatonin Receptor 1B). [provided by Alliance of Genome Resources, Apr 2022]
Mtnr1b Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_145712.2 | NP_663758.2 | melatonin receptor type 1B |
Mtnr1b Protein Structure
7tm_GPCRs: cl28897 (40 - 318)
7tm_GPCRs: cd14964 (42 - 66)
7tm_GPCRs: cd14964 (75 - 97)
7tm_GPCRs: cd14964 (113 - 135)
7tm_GPCRs: cd14964 (158 - 174)
7tm_GPCRs: cd14964 (197 - 220)
7tm_GPCRs: cd14964 (249 - 271)
7tm_GPCRs: cd14964 (286 - 311)
- 0
- 100
- 200
- 300
- 364 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
melatonin receptor type 1B |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS08806 | MTNR1B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS08807 | Mtnr1b Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS08808 | Mtnr1b Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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