Ivd - isovaleryl-CoA dehydrogenase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24513

Summary

Enables identical protein binding activity and isovaleryl-CoA dehydrogenase activity. Involved in leucine catabolic process. Located in mitochondrial matrix and mitochondrial membrane. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and isovaleric acidemia. Orthologous to human IVD (isovaleryl-CoA dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Ivd Products (1)

mRNA Protein Name
NM_012592.2 NP_036724.1 isovaleryl-CoA dehydrogenase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 3-methylbutanoyl-CoA dehydrogenase activity IDA
IDA: Inferred from direct assay
2777793 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
6401713 RGD
Biological Process GO Annotation Evidence References Source
involved in L-leucine catabolic process IDA
IDA: Inferred from direct assay
6401713 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
2777793 RGD
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
3813556 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

isovaleryl-CoA dehydrogenase, mitochondrial

  • butyryl-CoA dehydrogenase

  • isovaleryl coenzyme A dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06999 IVD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-D0932S Sudan IV-d6 / Unkown
HY-RS18896 Ivd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25387 Ivd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ivd NCBI NCBI:3712
Mus musculus Ivd NCBI NCBI:56357