Vav1 - vav guanine nucleotide exchange factor 1 Gene

Also Known as Vav

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25156

Summary

Predicted to enable guanyl-nucleotide exchange factor activity; phosphorylation-dependent protein binding activity; and phosphotyrosine residue binding activity. Involved in immune response-regulating cell surface receptor signaling pathway. Predicted to be located in cell-cell junction. Biomarker of endometriosis; hepatocellular carcinoma; lymphopenia; and type 1 diabetes mellitus. Orthologous to human VAV1 (vav guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Vav1 Products (1)

mRNA Protein Name
NM_012759.2 NP_036891.2 proto-oncogene vav

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in immune response-regulating cell surface receptor signaling pathway IEP
IEP: Inferred from expression pattern
1531699 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proto-oncogene vav

  • p95

  • vav 1 guanine nucleotide exchange factor

  • vav 1 oncogene

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-168625 MRT-6160 99.51% Unkown
HY-131598C 6-Thio-GTP tetrasodium Inhibitor 99.7% Unkown
HY-168624 VAV1 degrader-2 98.15% Unkown
HY-175453 MRT-23227 99.45% Unkown
HY-RS15612 VAV1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-179119 AB19 Inhibitor / Unkown
HY-182765 VAV1 degrader-4 / Unkown
HY-RS20834 Vav1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27348 Vav1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vav1 NCBI NCBI:7409