(R)-MRT-6160

(R)-MRT-6160 is a molecular glue degrader targeting VAV1, with a DC50 of 40.93 nM. (R)-MRT-6160 induces VAV1 ubiquitination and proteasomal degradation by forming a CRBN-(R)-MRT-6160-VAV1 ternary complex, thereby inhibiting signaling downstream of the T/B cell receptor. (R)-MRT-6160 can be used in leukemia-related research.

For research use only. We do not sell to patients.

  • CAS No.: 3050683-63-8
  • Formula: C22H17ClN2O3
  • Molecular Weight:392.84
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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