GATA1 - Gata1 GATA binding protein 1 Gene

Also Known as Eryf1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25172

Summary

Enables chromatin binding activity and sequence-specific DNA binding activity. Involved in several processes, including Sertoli cell development; cellular response to cAMP; and cellular response to follicle-stimulating hormone stimulus. Located in nucleus. Biomarker of mental depression and polycythemia. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; X-linked recessive disease (multiple); bone marrow Cancer (multiple); colon adenocarcinoma; and myeloid leukemia associated with Down Syndrome. Orthologous to human GATA1 (GATA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

GATA1 Products (1)

mRNA Protein Name
NM_012764.2 NP_036896.1 erythroid transcription factor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7957872 RGD
enables chromatin binding IDA
IDA: Inferred from direct assay
22885997 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
7957872 RGD
Biological Process GO Annotation Evidence References Source
involved in Sertoli cell development IEP
IEP: Inferred from expression pattern
9089398 RGD
involved in animal organ regeneration IDA
IDA: Inferred from direct assay
18990226 RGD
involved in cellular response to cAMP IEP
IEP: Inferred from expression pattern
11861504 RGD
involved in cellular response to follicle-stimulating hormone stimulus IEP
IEP: Inferred from expression pattern
11861504 RGD
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
17687519 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
22390417 RGD
involved in positive regulation of mast cell degranulation IMP
IMP: Inferred from mutant phenotype
22390417 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

erythroid transcription factor

  • GATA-1

  • GATA-binding factor 1

  • GATA-binding protein 1 (globin transcription factor 1)

  • GF-1

  • NF-E1 DNA-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P3761 Ac-Tyr-Val-Lys-Asp-aldehyde Inhibitor 99.89% Unkown
HY-RS05289 GATA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174677 Human GATA1 mRNA / Unkown
HY-RS20026 Gata1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26529 Gata1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens GATA1 NCBI NCBI:2623