P2ry1 - purinergic receptor P2Y1 Gene

Rattus norvegicus

Also known as P2y; P2y1

Gene ID: 25265 | Gene type: protein coding

About P2ry1

Primary_assembly 2: 145,241,849-145,248,457 forward strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 191 orthologues, 13 paralogues and is associated with 3 phenotypes. Biased expression in Muscle (RPKM 119.4), Spleen (RPKM 41.7) and 8 other tissues.

Summary

Enables several functions, including A1 Adenosine Receptor binding activity; G protein-coupled purinergic nucleotide receptor activity; and adenyl ribonucleotide binding activity. Involved in several processes, including purinergic nucleotide receptor signaling pathway; regulation of cytosolic calcium ion concentration; and regulation of secretion by cell. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and postsynaptic density. Is active in glutamatergic synapse. Is integral component of presynaptic active zone membrane. Colocalizes with mitochondrion. Used to study impotence. Orthologous to human P2RY1 (purinergic receptor P2Y1). [provided by Alliance of Genome Resources, Apr 2022]

P2ry1 Products(1)

mRNA	Protein	Name
NM_012800.3	NP_036932.1	P2Y purinoceptor 1

P2ry1 Protein Structure

7tmA_P2Y1

0
100
200
300
373 a.a.

Protein Preferred Names

Protein Names

P2Y purinoceptor 1

ATP receptor	P2 purinoreceptor subclass 2Y
P2Y ATP receptor 1	purinergic receptor P2Y, G-protein coupled, 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS09914	P2RY1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS09915	P2ry1 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS09916	P2ry1 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	P2ry1	NCBI	NCBI:5028
Mus musculus	P2ry1	NCBI	NCBI:18441

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