Cd247 - Cd247 molecule Gene

Also Known as Cd3z; TCRzeta

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25300

Summary

Predicted to enable identical protein binding activity and protein tyrosine kinase binding activity. Involved in cell surface receptor signaling pathway. Part of T cell receptor complex. Human ortholog(s) of this gene implicated in immunodeficiency 25. Orthologous to human CD247 (CD247 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd247 Products (2)

mRNA Protein Name
NM_001205304.1 NP_001192233.1 T-cell surface glycoprotein CD3 zeta chain isoform 2 precursor
NM_170789.2 NP_740770.2 T-cell surface glycoprotein CD3 zeta chain isoform 1 precursor
Biological Process GO Annotation Evidence References Source
involved in cell surface receptor signaling pathway IDA
IDA: Inferred from direct assay
8409430 RGD
Cellular Component GO Annotation Evidence References Source
part of T cell receptor complex IDA
IDA: Inferred from direct assay
8409430 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-cell surface glycoprotein CD3 zeta chain

  • CD247 antigen

  • CD3 antigen, zeta polypeptide

  • T-cell receptor CD3, subunit zeta

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd247 NCBI NCBI:919