Fgf10 - fibroblast growth factor 10 Gene

Also Known as Fgf5a; FGF-10

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25443

Summary

Predicted to enable heparin binding activity; receptor ligand activity; and type 2 Fibroblast Growth Factor receptor binding activity. Involved in several processes, including angiogenesis; response to estradiol; and response to lipopolysaccharide. Acts upstream of or within organ induction. Predicted to be located in cell surface; nucleus; and plasma membrane. Predicted to be active in cytoplasm and extracellular space. Predicted to colocalize with collagen-containing extracellular matrix. Biomarker of hypospadias. Human ortholog(s) of this gene implicated in LADD syndrome and aplasia of lacrimal and salivary glands. Orthologous to human FGF10 (Fibroblast Growth Factor 10). [provided by Alliance of Genome Resources, Apr 2022]

Fgf10 Products (1)

mRNA Protein Name
NM_012951.2 NP_037083.1 fibroblast growth factor 10 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in angiogenesis IEP
IEP: Inferred from expression pattern
12565793 RGD
involved in cell differentiation IEP
IEP: Inferred from expression pattern
12565793 RGD
acts upstream of or within organ induction IDA
IDA: Inferred from direct assay
10964474 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
15680359 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
19524256 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
19464577 RGD
involved in tissue regeneration IEP
IEP: Inferred from expression pattern
12565793 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 10

  • fibroblast growth factor 5a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04887 FGF10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174711 Human FGF10 mRNA / Unkown
HY-RS16590 Fgf10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23025 Fgf10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991584 HuGAL-FR21 Inhibitor 97.80% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf10 NCBI NCBI:2255