Il1rap - interleukin 1 receptor accessory protein Gene

Also Known as IL-1RAcp; Il1racpb

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25466

Summary

Enables interleukin-1 receptor binding activity. Predicted to be involved in several processes, including interleukin-33-mediated signaling pathway; positive regulation of cytokine production; and regulation of synapse assembly. Predicted to act upstream of or within cytokine-mediated signaling pathway and positive regulation of dendrite development. Located in cytoplasm. Part of protein-containing complex. Orthologous to human IL1RAP (interleukin 1 receptor accessory protein). [provided by Alliance of Genome Resources, Apr 2022]

Il1rap Products (2)

mRNA Protein Name
NM_001167840.2 NP_001161312.1 interleukin-1 receptor accessory protein isoform b precursor
NM_012968.1 NP_037100.1 interleukin-1 receptor accessory protein precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables interleukin-1 receptor binding IPI
IPI: Inferred from physical interaction
21314939 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
21314939 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-1 receptor accessory protein

  • IL-1 receptor accessory protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99379 Nidanilimab (Nadunolimab) Inhibitor 99.90% Phase 2
HY-P991267 CAN10 Inhibitor 95.04% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06722 IL1RAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24078 Il1rap Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17618 Il1rap Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992026 ADV-101 Antibody / Unkown
HY-P992027 CSC012 Antibidy / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il1rap NCBI NCBI:3556