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Nidanilimab (Nadunolimab)

(Synonyms: CAN04; Anti-IL-1RAP/IL-1R3 Reference Antibody (nidanilimab))
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Nidanilimab (CAN04) is a fully humanized monoclonal anti-IL1RAP antibody with a Kd value of 1.10 pM. Nidanilimab blocks IL1α and IL1β signaling and stimulates the immune system to destroy tumour cells. Nidanilimab can be used in research of non-small lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC) .

For research use only. We do not sell to patients.

  • Purity: 99.90%
  • CAS No.: 2171061-85-9
  • Molecular Weight:144.3 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Nidanilimab (Nadunolimab)
  • Experimental Validation Results for Nidanilimab (Nadunolimab)
  • Experimental Validation Results for Nidanilimab (Nadunolimab)
  • Nidanilimab (Nadunolimab) Chemical Structure
    Nidanilimab (Nadunolimab) Chemical Structure
CAS No.: 2171061-85-9
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Nidanilimab (Nadunolimab) Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All Interleukin Related Isoforms

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human IL1RAP/IL-1RAcP Protein (His Tag) can bind Nidanilimab. The EC50 for this effect is 1.80 ng/mL.

  • 1/16

    Loaded Nidanilimab (Nadunolimab) on AHC2 biosensor, can bind IL-1RAcP/IL-1 R3 Protein, Human (339a.a, HEK293, His, HY-P72565) with an affinity constant of 5.812E-10 M as determined in BLI assay.

  • Nidanilimab (Nadunolimab) Chemical Structure
    1/16
  • Nidanilimab (Nadunolimab)
  • Immobilized Human IL1RAP/IL-1RAcP Protein (His Tag) can bind Nidanilimab. The EC50 for this effect is 1.80 ng/mL.
  • Loaded Nidanilimab (Nadunolimab) on AHC2 biosensor, can bind IL-1RAcP/IL-1 R3 Protein, Human (339a.a, HEK293, His, HY-P72565) with an affinity constant of 5.812E-10 M as determined in BLI assay.