Ube2i - ubiquitin-conjugating enzyme E2I Gene

Also Known as UbcE2A

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25573

Summary

Enables bHLH transcription factor binding activity; protein C-terminus binding activity; and ubiquitin-like protein transferase activity. Involved in cellular protein metabolic process; positive regulation of DNA-binding transcription factor activity; and regulation of signal transduction. Located in dendrite; nucleus; and synapse. Orthologous to human UBE2I (Ubiquitin Conjugating Enzyme E2 I). [provided by Alliance of Genome Resources, Apr 2022]

Ube2i Products (1)

mRNA Protein Name
NM_013050.2 NP_037182.1 SUMO-conjugating enzyme UBC9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SUMO transferase activity IDA
IDA: Inferred from direct assay
11812797 RGD
enables bHLH transcription factor binding IPI
IPI: Inferred from physical interaction
9013644 RGD
enables ionotropic glutamate receptor binding IPI
IPI: Inferred from physical interaction
17486098 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9497385 RGD
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
9013644 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
11812797 RGD
involved in positive regulation of intracellular steroid hormone receptor signaling pathway IDA
IDA: Inferred from direct assay
11812797 RGD
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
9013644 RGD
involved in protein sumoylation IDA
IDA: Inferred from direct assay
11812797 RGD
involved in regulation of signaling receptor activity IDA
IDA: Inferred from direct assay
11812797 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
17486098 RGD
located in fibrillar center IDA
IDA: Inferred from direct assay
17587596 RGD
located in nuclear body IDA
IDA: Inferred from direct assay
17549507 RGD
located in nuclear envelope IDA
IDA: Inferred from direct assay
9497385 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SUMO-conjugating enzyme UBC9

  • RING-type E3 SUMO transferase UBC9

  • SUMO-protein ligase

  • Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9)

  • ubiquitin carrier protein 9

  • ubiquitin carrier protein I

  • ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)

  • ubiquitin-conjugating e

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15349 UBE2I Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18848 Ube2i Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25340 Ube2i Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube2i NCBI NCBI:7329